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Profile of Dr. Rika Indri Astuti S.Si., M.Si.

Personal Information

Full Name Dr. Rika Indri Astuti S.Si., M.Si.
E-mail rikaindriastuti [at] apps.ipb.ac.id
Website https://www.scopus.com/authid/detail.uri?authorId=45260930400
Division Microbiology
Research Interest
  • Microbial signal transduction on stress response
  • Bioethanol production from engineered yeast
  • Study of cellular aging in yeast model
  • Yeast-based biosensors for heavy metal and toxin detection
Google Scholar Profile

Education

Degree Major University
S1 Biology IPB
S2 Biology IPB
S3 Microbiology Nara Institute of Science and Technology

Researches

Research Year
Pengembangan Galur Khamir Etanologenik
2023
Bacterial metabolites and flavonoid from clove as antigenotoxic agents
2021-2023
Bioprocess engineering for ethanol production by thermotolerant yeast based on metabolomic approach
2021

2021

2020
Molecular Pharmacology of Clove-derived Anti-aging agent: Study in Yeast
2018-2020
Yeast application for industry
2018-2020

2017-2018

Research collaboration within Global Collaborative Research scheme, fiscal year 2017, with Nara Institute of Science and Technology
2017

Research collaboration within Global Collaborative Research scheme, fiscal year 2016, with Nara Institute of Science and Technology
2016-2017
Significance role of nitric oxide in yeast Schizosaccaromyces pombe
2012-2015
Colonization of Soybean Root By Biocontrol Strain Pseudomonas sp. Crb-34 using GFP
2010-2011
Technology development of rhizobacteria as biofertilizer and biofungicide
2010-2011
Disease suppression of fungal phytopathogens by siderophore-producing Pseudomonas
2009-2010

Publications

Title Year
Bioethanol Production from Non-Conventional Yeasts Wickerhamomyces anomalus (Pichia anomala) and Detection of ADH1 Gene
MF Fathiah, FD Hartono, RI Astuti, S Listiyowati, A Meryandini
HAYATI Journal of Biosciences 31 (2), 221-228, 2024
2024
Phytochemical Profiling of Hippobroma longiflora Leaf Extract Using LC-MS/MS Analysis and Pharmacological Potential
A Burhan, D Ratnadewi, A Setiyono, RI Astuti, AH Umar
Egyptian Journal of Chemistry, 2024
2024
The Antibacterial and Antibiofilm Activities of the Endophytic Bacteria Associated with Archidendron pauciflorum against Multidrug-Resistant Strains
JA Priyanto, ME Prastya, RI Astuti, R Kristiana
Applied Biochemistry and Biotechnology, 1-22, 2023
2023
Current trends and future perspective of probiotic yeasts research in Indonesia
RI Astuti, ME Prastya, R Wulan, K Anam, A Meryandini
FEMS Yeast Research, foad013, 2023
2023
Profile of Gut Bacteria in Hypertensive Patients Based on Terminal Restriction Fragment Length Polymorphism Analysis
RH Putri, RI Astuti, S Budiarti
HAYATI Journal of Biosciences 30 (3), 500-509, 2023
2023
Quercetin-Containing Extract from Clove Syzygium aromaticum L. Endophytic Bacteria, Fictibacillus phosphorivorans P1U2, Exhibits Antimutagenic Activity in Yeast Saccharomyces …
NF Ashafani, RI Astuti, S Listiyowati, I Batubara
HAYATI Journal of Biosciences 30 (4), 734-742, 2023
2023
Metabolomics Study Reveals Biomarker L-Proline as Potential Stress-Protectant Compound for High-Temperature Bioethanol Fermentation by Yeast Pichia kudriavzevii 1P4
H Khotimah, RI Astuti, M Rafi, ND Yuliana
Applied Biochemistry and Biotechnology, 1-19, 2023
2023
Endophytic bacteria of clove (Syzygium aromaticum L.) leaves produce metabolites with antioxidant and antiaging properties
LA Utami, WT Wahyuni, NR Mubarik, RI Astuti
Journal of Applied Pharmaceutical Science, 2023
2023
Bioactivity of the Ethanol Extract of Clove (Syzygium aromaticum) as Antitoxin
E Afrendi, ME Prastya, RI Astuti, WT Wahyuni, I Batubara
International Journal of Food Science 2023, 2023
2023
Streptomyces–Alginate Beads Formula Promote Maize Plant Growth and Modify the Rhizosphere Microbiome.
O Asriatno, AA Nawangsih, RI Astuti, AT Wahyudi
Jordan Journal of Biological Sciences 16 (3), 2023
2023
Endophytic bacteria of clove (Syzygium aromaticum L.) leaves produce metabolites with antioxidant and anti-aging properties
LA Utami, WT Wahyuni, NR Mubarik, RI Astuti
Journal of Applied Pharmaceutical Science 13 (7), 241-250, 2023
2023
Antioxidant Properties of Active Fraction Extract Derived from Yellow-Red Pigment Produced by the Marine Sponge-Associated Bacterium Bacillus haikouensis AGS112 and …
U Cahlia, RI Astuti, J Nomura, AT Wahyudi
HAYATI Journal of Biosciences 30 (5), 874-884, 2023
2023
Production of codon-optimized Factor C fragment from Tachypleus gigas in the Pichia pastoris GS115 expression system for endotoxin detection
Z Bachtiar, AZ Mustopa, RI Astuti, F Fauziyah, F Fatimah, R Rozirwan, ...
Journal of Genetic Engineering and Biotechnology 21 (1), 103, 2023
2023
Bioactivity of the Ethanol Extract of Clove
E Afrendi, ME Prastya, RI Astuti, WT Wahyuni, I Batubara
2023
Expression of recombinant human insulin precursor by Pichia pastoris in a 10 liter bioreactor
DJ Puspitasari, AH Mahsunah, D Nurdiani, RI Astuti, A Meryandini
IOP Conference Series: Earth and Environmental Science 1271 (1), 012092, 2023
2023
The clove essential oil and its combination with galangal oil exhibit antibacterial activity, potential as antiseptic agent
RR Dany, RI Astuti, JA Priyanto
IOP Conference Series: Earth and Environmental Science 1271 (1), 012076, 2023
2023
Endophytic Bacillus spp. isolated from Archidendron pauciflorum: Pharmacological property and their phytochemical constituents.
JA PRIYANTO, ME PRASTYA, RI ASTUTI, T MOZEF
Journal of Research in Pharmacy 27 (6), 2023
2023
Apoptosis in Yeast is Modulated by Clove Leaf Extract and Eugenol Potentially by Interfering Caspase YCA1
A Septyani, A Rika Indri, B Irmanida
Online Journal of Biological Science 22 (3), 388-394, 2022
2022
Antioxidant Activity of Endophytic Bacteria Derived from Hoya multiflora Blume Plant and Their Cellular Activities on Schizosaccharomyces pombe
NTG Pudjas, NR Mubarik, RI Astuti, LI Sudirman
HAYATI Journal of Biosciences 29 (2), 214-221, 2022
2022
Skrining dan Identifikasi Bakteri Laut Penghasil Enzim Selulase yang Berasosiasi dengan Spons
RI Astuti, YBP Saju, D Aribah, AT Wahyudi
Jurnal Ilmu Pertanian Indonesia 27 (1), 70-75, 2022
2022
Waste to Wealth: The Importance of Yeasts in Sustainable Bioethanol Production from Lignocellulosic Biomass
A Watcharawipas, NSB Mat Nanyan, RI Astuti
Waste Management, Processing and Valorisation, 265-283, 2022
2022
Seleksi, Karakterisasi Morfologi, dan Identifikasi Aktinobakteri Penghasil Mananase Asal Hutan Tanah Jambi untuk Produksi Mananoligosakarida
R Wulan, RI Astuti, Y Rukayadi, S Estuningsih, A Meryandini
Jurnal Ilmu Pertanian Indonesia 27 (2), 279-286, 2022
2022
Natural extracts derived from marine sponge-associated bacteria with diverse nonribosomal peptide synthetase genes have anticancer activities
JA Priyanto, WE Purwaningtyas, D Ferantika, D Tohir, RI Astuti, ...
Journal of Applied Pharmaceutical Science 12 (04), 054-063, 2022
2022
Ethanol Productivity of Ethanol-Tolerant Mutant Strain Pichia kudriavzevii R-T3 in Monoculture and Co-culture Fermentation with Saccharomyces cerevisiae
N Rahmadhani, RI Astuti, A Meryandini
HAYATI Journal of Biosciences 29 (4), 435-444, 2022
2022
Metode Eksperimen dalam Genetika Bakteri
AT Wahyudi, RI Astuti, JA Priyanto
PT Penerbit IPB Press, 2022
2022
An orange pigment from the marine bacterium Paracoccus haeundaensis SAB E11 as a prospective source of natural antioxidants
H ABUBAKAR, RI ASTUTI, SRI LISTYOWATI, I BATUBARA, ...
Biodiversitas Journal of Biological Diversity 23 (9), 2022
2022
Diversitas Pangan Fermentasi Berbasis-Susu di Indonesia dan Kandungan Gizinya
FN Nabilah, S Listiyowati, RI Astuti
Jurnal Ilmu Pertanian Indonesia 27 (4), 552-561, 2022
2022
APPLICATION OF RECOMBINANT TRIACYLGLYCEROL LIPASE AND CARBOXYLESTERASE ENZYMES FROM Bacillus velezensis STRAIN S3 FOR POLYESTER SURFACE MODIFICATION
IR Layly, I Helianti, RI Astuti, A Meryandini
Jurnal Bioteknologi & Biosains Indonesia (JBBI) 9 (2), 179-190, 2022
2022
Cell Longevity of Yeast Saccharomyces cerevisiae by Clove Bud Extract Treatment May Occur in Sirtuin-Independent Pathway
A Zahrah Qolbaina, A Rika Indri, L Sri
Online Journal of Biological Sciences 21 (3), 271-278, 2021
2021
Antiaging Properties of the Ethanol Fractions of Clove (Syzygium aromaticum L.) Bud and Leaf at the Cellular Levels: Study in Yeast Schizosaccharomyces pombe
D Lesmana, D Andrianto, RI Astuti
Scientia Pharmaceutica 89 (4), 45, 2021
2021
Antiaging and Skin Irritation Potential of Four Main Indonesian Essential Oils
D Rahmi, R Yunilawati, BN Jati, I Setiawati, A Riyanto, I Batubara, ...
Cosmetics 8 (4), 94, 2021
2021
Identification of lipase producing bacteria from palm oil sewage sludge processing plant at Malimping, Banten, Indonesia
IR Layly, A MERYANDINI, IS HELIANTI, RI ASTUTI
Biodiversitas Journal of Biological Diversity 22 (10), 2021
2021
Methanol pigment extracts derived from two marine actinomycetes exhibit antibacterial and antioxidant activities
DK MESRIAN, WE PURWANINGTYAS, RI ASTUTI, AEZ HASAN, ...
Biodiversitas Journal of Biological Diversity 22 (10), 2021
2021
Antiaging and Antioxidant Bioactivities of Asteraceae Plant Fractions on the Cellular Functions of the Yeast Schizosaccharomyces pombe
RI Astuti, ME Prastya, I Batubara, E Budiarti, A Ilmiyawati
Advances in pharmacological and pharmaceutical sciences 2021, 2021
2021
Evaluation of Indigenous Pichia kudriavzevii from cocoa fermentation for a probiotic candidate
R Wulan, RI Astuti, Y Rukayadi, A Meryandini
Biodiversitas Journal of Biological Diversity 22 (3), 2021
2021
Anti-Aging Activity of Xylocarpus Granatum Phytoextracts and Xyloccensins K Compound
SM Yusuf, RI Astuti, I Batubara, W Chavasiri
Indonesian Journal of Pharmacy, 365-375, 2021
2021
Yeasts Isolated from Traditional Brem Bali Show Stress Tolerance Phenotype against Fermentation-Related Stresses
AB Lenka, RI Astuti, S Listiyowati
Makara Journal of Science 25 (1), 7, 2021
2021
Antiaging and Skin Irritation Potential of Four Main Indonesian Essential Oils. Cosmetics 2021, 8, 94
D Rahmi, R Yunilawati, BN Jati, I Setiawati, A Riyanto, I Batubara, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
2021
Activity of Ethanol-derived Fraction of Clove Leaves and Eugenol Compound as Antiaging Agent in the Yeast Model Organism Schizosaccharomyces pombe
SA Anwar, RI Astuti, DD Solihin
3rd KOBI Congress, International and National Conferences (KOBICINC 2020 …, 2021
2021
The antiaging effect of active fractions and ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic acid isolated from adenostemma lavenia (L.) o. kuntze at the cellular level
I Batubara, RI Astuti, ME Prastya, A Ilmiawati, M Maeda, M Suzuki, ...
Antioxidants 9 (8), 719, 2020
2020
Substrate utilization of ethanologenic yeasts co-cultivation of Pichia kudriavzevii and Saccharomyces cerevisiae
N Rahmadhani, RI Astuti, A Meryandini
IOP Conference Series: Earth and Environmental Science 457 (1), 012072, 2020
2020
The ethanol production activity of indigenous thermotolerant yeast Pichia kudriavzevii 1P4
D ULYA, RI ASTUTI, A MERYANDINI
Microbiology Indonesia 14 (4), 1-1, 2020
2020
Enhanced Ethanol Production by High Temperature-Tolerance Mutant Pichia kudriavzevii T-T2 in various Carbon and Nitrogen Sources
MONICA INA MAR THA , RIKA INDRI ASTUTI , AND WULAN TRI W AHYUNI
Microbiology Indonesia
2020
Natural extract and its fractions isolated from the marine bacterium Pseudoalteromonas flavipulchra STILL-33 have antioxidant and antiaging activities in Schizosaccharomyces pombe
Muhammad Eka Prastya, Rika Indri Astuti, Irmanida Batubara, Hiroshi Takagi, Aris Tri Wahyudi
FEMS Yeast Research
2020
Screening and characterization of sponge-associated bacteria from Seribu Island, Indonesia producing cellulase and laccase enzymes
WENANG MAHARSIWI , RIKA INDRI ASTUTI, A NJA MERYANDINI, ARIS TRI WAHYUDI
Biodiversitas
2020
The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular Level
Irmanida Batubara, Rika Indri Astuti, Muhammad Eka Prastya, Auliya Ilmiawati,Miwa Maeda, Mayu Suzuki, Akie Hamamoto and Hiroshi Takemori
Antioxidants
2020
Substrate utilization of ethanologenic yeasts co-cultivation ofPichiakudriavzeviiand Saccharomyces cerevisiae
Nurfadhilla Ramadhani, Rika Indri Astuti*, Anja Meryandini
IOP Proceeding Series
2020
The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular …
I Batubara, RI Astuti, ME Prastya, A Ilmiawati, M Maeda, M Suzuki, ...
Antioxidants 9 (8), 719, 2020
2020
Effect of Ethanol-Derived Clove Leaf Extract on the Oxidative Stress Response in Yeast Schizosaccharomyces pombe
AF Fauzya, RI Astuti, NR Mubarik
International Journal of Microbiology 2019, 2019
2019
Modulation of Aging in Yeast Saccharomyces cerevisiae by Roselle Petal Extract (Hibiscus sabdariffa L.)
RIA Sarima, A Meryandini
2019
Antioxidant, Antiglycation and in vivo Antiaging Effects of Metabolite Extracts from Marine Sponge-associated Bacteria.
ME Prastya, RI ASTUTI, I Batubara, AT Wahyudi
Indian Journal of Pharmaceutical Sciences 81 (2), 2019
2019
Plant Growth Promoting Activity of Actinomycetes Isolated from Soybean Rhizosphere
RIAAA Aris Tri Wahyudi, Jepri Agung Priyanto, Resti Afrista, Deni Kurniati
Online Journal of Biological Science 19 (1), 1-8, 2019
2019
Antioxidant, antiglycation and in vivo antiaging effects of metabolite extracts from marine sponge-associated bacteria
ME Prastya, RI Astuti, I Batubara, AT Wahyudi
Indian Journal of Pharmaceutical Sciences 81 (2), 344-353, 2019
2019
Life span extension of model yeast Saccharomyces cerevisiae upon ethanol derived-clover bud extract treatment
RI Astuti, S Listyowati, WT Wahyuni
IOP Conference Series: Earth and Environmental Science 299 (1), 012059, 2019
2019
Characterization of Exon and Intron of Defensin 1 Gene in Apis cerana and Apis dorsata
A Alfiyan, R Raffiudin, RI Astuti
Makara Journal of Science 23 (3), 3, 2019
2019
Metagenomic Analysis of Bacteria Phylum Firmicutes and Bacteroidetes in Women with Type 2 Diabetes
Z Zulhaerati, S Budiarti, RI Astuti
HAYATI Journal of Biosciences 26 (3), 110-116, 2019
2019
IN VITRO ANTIBACTERIAL ACTIVITIES OF MARINE SPONGE-ASSOCIATED BACTERIA AGAINST PATHOGENIC VIBRIO SPP. CAUSES VIBRIOSIS IN SHRIMPS
ATRI WAHYUDI, JA PRIYANTO, DR WULANDARI, RI ASTUTI
International Journal of Pharmacy and Pharmaceutical Sciences, 33-37, 2019
2019
Chemical screening identifies an extract from marine Pseudomonas sp.-PTR-08 as an anti-aging agent that promotes fission yeast longevity by modulating the Pap1–ctt1+ pathway …
ME Prastya, RI Astuti, I Batubara, H Takagi, AT Wahyudi
Molecular biology reports, 1-11, 2019
2019
Bacillus sp. SAB E-41-derived extract shows antiaging properties via ctt1-mediated oxidative stress tolerance response in yeast Schizosaccharomyces pombe
ME Prastya, RI Astuti, I Batubara, AT Wahyudi
Asian Pacific Journal of Tropical Biomedicine 8 (11), 533, 2018
2018
Exogenous L-proline Increases Stress Tolerance of Yeast Pichia kudriavzevii Against Inhibitors in Lignocellulose Hydrolysates and Enhances its Ethanol Production
RI Astuti, N Nurhayati, S Alifiyanti, TC Sunarti, A Meryandini
IOP Conference Series: Earth and Environmental Science 197 (1), 012052, 2018
2018
Nitric oxide signalling in yeast
RI Astuti, R Nasuno, H Takagi
Advances in microbial physiology 72, 29-63, 2018
2018
Screening and Characterization of Sponge-Associated Bacteria Producing Bioactive Compounds Anti-Vibrio sp.
WMRIA Aris Tri Wahyudi, Jepri Agung Priyanto
American Journal of Biochemistry and Biotechnology 14 (3), 221-229, 2018
2018
Diversity of urinary tract infection bacteria in children in Indonesia based on metagenomic approach
G CHRISTINE, SRI BUDIARTI, RI ASTUTI
Biodiversitas Journal of Biological Diversity
2018
Nitric Oxide Signaling in Yeast
Astuti, R.I., Nasuno, R., Takagi, H.
Advances in Microbial Physiology
2018
Ethanol Production by Novel Proline Accumulating Pichia kudriavzevii Mutants Strains Tolerant to High Temperature and Ethanol Stresses
Rika Indri Astuti, Sena Alifianti, Ratu Nabila Maisyitoh, Nisa Rachmania Mubarik and Anja Meryandini
OnLine Journal of Biological Sciences
2018
Leaf blast disease reduction by rice-phyllosphere actinomycetes producing bioactive compounds
W Harsonowati, RI Astuti, AT Wahyudi
Journal of General Plant Pathology 83 (2), 98-108
2017
Bioactive compounds from sponge associated bacteria: Anticancer activity and NRPS-PKS gene expression in different carbon sources
Priyanto, J.A., Astuti, R.I., Nomura, J., Wahyudi, A.T.
American Journal of Biochemistry and Biotechnology
2017
Nitric oxide signaling and its role in oxidative stress response in Schizosaccharomyces pombe
Rika Indri Astuti, Daisuke Watanabe, Takagi Hiroshi
Nitric Oxide
2016
Nitric oxide (NO) signaling and its importance in oxidative stress response in the fission yeast Schizosaccharomyces pombe
RI Astuti
Nara Institute of Science and Technology, 2015
2015
The role of nitric oxide in the fission yeast Schizosaccharomyces pombe under oxidative stress conditions
RI Astuti, H Takagi
Nitric Oxide, 115, 2014
2014
Detection and Cloning of a Gene Involved in Zwitermicin A Synthesis from Plant Growth Promoting Rhizobacteria of Bacillus sp CR64
AT Wahyudi, RI Astuti, NR Mubarik, SA Faulina
Indonesian Journal of Biotechnology 15 (1), 2013
2013
Screening of Pseudomonas sp. isolated from rhizosphere of soybean plant as plant growth promoter and biocontrol agent.
AT Wahyudi, RI Astuti
American Journal of Agricultural and Biological Sciences 6 (1), 134-141, 2011
2011
Screening of< i> Pseudomonas sp. Isolated from Rhizosphere of Soybean Plant as Plant Growth Promoter and Biocontrol Agent
AT Wahyudi, RI Astuti
American Journal of Agricultural and Biological Sciences 6 (1), 134, 2011
2011
Detection and cloning of a gene involved in zwitermicin a biosynthesis from plant growth promoting rhizobacterium Bacillus sp. CR64
AT Wahyudi, RI Astuti, N Rachmania, SA Faulina
Indones J Biotechnol, 2010
2010
Screening of Pseudomonas sp. isolated from rhizosphere of soybean plant as plant growth promoter and biocontrol agent
AT Wahyudi, RI Astuti
IPB (Bogor Agricultural University), 2010
2010
Analisis karakter pseudomonas sp. sebagai agen pemacu pertumbuhan tanaman dan biokontrol fungi patogen
RI Astuti
IPB (Bogor Agricultural University), 2008
2008
Cloning of Genomic DNA Fragment Involved in Acid-Aluminium Tolerance in Bradyrhizobium japonicum 38 Through Transposon Mutagenesis
RI Astuti, AT Wahyudi, NR Mubarik
Microbiology Indonesia 11 (1), 2006
2006
Kloning fragmen DNA genom yang terlibat dalam toleransi asam-alumunium pada Bradyrhizobium japonicum melalui mutagenesis dengan transposon
RI Astuti
IPB (Bogor Agricultural University), 2006
2006
KLONING FRAGMEN DNA GENOM YANG TERLIBAT DALAM TOLERANSI ASAM-ALUMINIUM PADA BRADYRHIZOBIUM JAPONICUM
RI Astuti, D Monasari, SA Faulina
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